Substance
"Substance" carries multiple distinct meanings across philosophy, science, and everyday language, each fundamental in its own way.
Meanings
Substance (philosophy) — that which persists through change; the underlying reality beneath appearances
Substance (chemistry) — matter with a definite composition, whether elemental or compound
Substance (psychology) — psychoactive chemicals affecting consciousness and behavior
Substance (rhetoric) — meaningful content; the weight of an argument versus its form
Related
Identity, Natural Resources, Inertia, The universe's structure, Careful observation